Guidelines

Which statins interact with verapamil?

Which statins interact with verapamil?

If you are taking verapamil with lovastatin or simvastatin, the amount of cholesterol medicine in your blood may increase and cause muscle problems. If you are taking atorvastatin and verapamil, the amount of verapamil in your blood may increase and cause more side effects than normal.

What drugs should not be taken with Zocor?

Some products that may interact with this drug include: “blood thinners” (such as warfarin), cyclosporine, danazol, daptomycin, gemfibrozil. Other medications can affect the removal of simvastatin from your body, which may affect how simvastatin works.

Can you take verapamil and lovastatin together?

Which is better Lipitor or Zocor?

Both Lipitor and Zocor are good for lowering LDL, but Zocor is better at increasing HDL and tends to have fewer gastrointestinal side effects, according to one study.

What vitamins should not be taken with atorvastatin?

A magnesium- and aluminum-containing antacid was reported to interfere with atorvastatin absorption. People can avoid this interaction by taking atorvastatin two hours before or after any aluminum/magnesium-containing antacids. Some magnesium supplements such as magnesium hydroxide are also antacids.

What medications should not be taken with verapamil?

Common medications that may interact with verapamil include:

  • alpha-blockers, such as prazosin.
  • anticonvulsants, such as carbamazepine, phenytoin, or phenobarbital.
  • antidepressants, such as nefazodone.
  • antifungal agents, such as itraconazole and ketoconazole.

How does verapamil interact with Zocor and Mevacor?

Please note that this is a major difference! The proposed mechanism is verapamil inhibition of Zocor metabolism via intestinal and hepatic CYP450 3A4. Although not studied, the interaction is also expected to occur with Mevacor due to its similar metabolic profile to Zocor.

What happens if you take Zocor with other medications?

Does ZOCOR Interact with other Medications? These medications are not usually taken together. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation. These medications may interact and cause very harmful effects. Consult your healthcare professional (e.g., doctor or pharmacist) for more in formation.

What happens when you take verapamil with a statin?

Verapamil use with Statins – Special Concern. Co-administration with verapamil may significantly increase the plasma concentrations of Zocor® and Mevacor® and potentiate the risk of statin-induced myopathy according to the Study of the Effectiveness of Additional Reductions in Cholesterol and Homocysteine (SEARCH).

Are there any drug interactions with simvastatin?

Dose reductions may be considered for atorvastatin, simvastatin, and lovastatin, given the potential for interactions mediated by both CYP3A4 and permeability glycoprotein (P-gp) pathways.