What is stromal dystrophy?
Congenital stromal corneal dystrophy is an inherited eye disorder. This condition primarily affects the cornea, which is the clear outer covering of the eye. In people with this condition, the cornea appears cloudy and may have an irregular surface.
What is the most common stromal dystrophy?
LATTICE CORNEAL DYSTROPHY. Lattice corneal dystrophy (LCD) is the most common of the corneal epithelial-stromal dystrophies. It is typically an autosomal dominant, bilateral disease that typically presents toward the end of the first decade of life with symptoms of recurrent corneal erosions and decreased vision.
Is corneal dystrophy curable?
Corneal dystrophy is an inherited condition, which means prevention is a mystery. The good news is that this condition is treatable.
How fast does Fuchs dystrophy progress?
It can take up to six months until full improvement in your vision is seen. DSEK and DMEK generally have short recovery times, usually only a few weeks or months and the risk of having the new corneal graft being rejected after surgery is also low.
Which is autosomal recessive inheritance of corneal stromal dystrophy?
Also known as Groenouw corneal dystrophy type II or Fehr spotted dystrophy. Autosomal recessive inheritance of the Carbohydrate sulfotransferase 6 gene (CHST) on 16q22. Stromal opacities with indistinct borders and intervening haze that may extend from limbus to limbus and through all layers of the cornea.
How are the three types of stromal dystrophies classified?
Classically, the stromal corneal dystrophies have been classified based on their phenotypic appearance at the slit lamp and divided into the three main types of granular, lattice, and macular.
What are the symptoms of corneal stromal dystrophy?
On electron microscopy the deposits appear as electron-dense, randomly aligned fibrils, 8-10nm in diameter. Symptoms of surface erosions, irregular astigmatism, and vision loss usually begin in the 2nd or 3rd decades of life. The recurrent erosions in lattice dystrophy may be frequent.
Which is autosomal dominant inheritance of lattice dystrophy?
Also know as Biber-Haab-Dimmer corneal dystrophy, TGFBI type Lattice Dystrophy, or Classic Lattice Dystrophy. Autosomal dominant inheritance of the TGFBI gene on the 5q31 locus. Lattice dystrophy may be quite variable in its appearance, but it is most typically marked by ‘glass-like’ filamentous lesions.