What is hitts syndrome?
Heparin-induced thrombocytopenia and thrombosis syndrome (HITTS) is an immune-mediated response to the administration of heparin that results in life-threatening thrombosis. The pathophysiology of HITTS remains controversial.
WHAT IS A HIT antibody?
A test for heparin-induced thrombocytopenia (HIT) antibody, also called heparin-PF4 antibody, is performed to detect antibodies that develop in some people who have been treated with heparin.
What is heparin induced thrombocytopenia?
Heparin‐induced thrombocytopenia (HIT) is a potentially devastating immune mediated adverse drug reaction caused by the emergence of antibodies that activate platelets in the presence of heparin.
Why do people get heparin-induced thrombocytopenia?
Heparin-induced thrombocytopenia (HIT) is caused by antibodies that bind to complexes of heparin and platelet factor 4 (PF4), activating the platelets and promoting a prothrombotic state. HIT is more frequently encountered with unfractionated heparin (UFH) than with low molecular weight heparin (LMWH).
What is the primary purpose of the Hitt program?
The HITT program’s primary purpose is to enhance operational fitness levels and optimize combat readiness and resiliency for the active duty and reservist Marine.
Which is the best Hitt program for Marines?
High Intensity Tactical Training Semper Fit’s High Intensity Tactical Training Program is a comprehensive, combat-focused Strength and Conditioning program specifically for Marines. HITT offers Marines elite resources, experts, and programs – all aimed to make Marines COMBAT FIT.
What do you mean by HIT Type II?
HIT type II, an immune-mediated syndrome caused by an antibody to the PF4/heparin complex — what we mean when we say “HIT” PF4 is released on platelet activation -> binds anionic glycosaminoglycans on cell surfaces -> inhibit the formation of megakaryocytes and angiogenesis + modulate immune response.