What is hepatic Acinus?
The hepatic acinus is the functional unit of the liver. As seen overlayed onto lobules in the diagram below, the acinus consists of an irregular shaped, roughly ellipsoidal mass of hepatocytes aligned around the hepatic arterioles and portal venules just as they anastomose into sinusoids.
What is the hepatic lobules function?
The structure of the liver’s functional units or lobules. Blood enters the lobules through branches of the portal vein and hepatic artery proper, then flows through sinusoids. The lobules of liver, or hepatic lobules, are small divisions of the liver defined at the microscopic (histological) scale.
What causes porta hepatis?
Other causes of periportal lymphadenopathy include infections such as tuberculosis and hepatitis B and C viruses and noninfectious inflammatory conditions such as autoimmune diseases and sarcoidosis (55) (Fig 16). Bulky lymphadenopathy in the porta hepatis can result in biliary obstruction (54).
How is the liver attached to the diaphragm?
Coronary ligament (anterior and posterior folds) – attaches the superior surface of the liver to the inferior surface of the diaphragm and demarcates the bare area of the liver The anterior and posterior folds unite to form the triangular ligaments on the right and left lobes of the liver.
Which liver zone is affected by alcohol?
Centrilobular hypoxia Liver injury is most prominent in the zonal region surrounding the central vein. This area is furthest from oxygenated blood and has the highest concentration of CYP2E1, suggesting that oxygen debt contributes to injury (Figure 12).
Do liver sinusoids contain bile?
Liver cells, or hepatocytes, have direct access to the liver’s blood supply through small capillaries called sinusoids. Hepatocytes carry out many metabolic functions, including the production of bile.
What do hepatic cells produce?
The hepatocyte is a cell in the body that manufactures serum albumin, fibrinogen, and the prothrombin group of clotting factors (except for Factors 3 and 4). It is the main site for the synthesis of lipoproteins, ceruloplasmin, transferrin, complement, and glycoproteins.
What does the hepatic portal triad consist of?
Portal triads are composed of three major tubes. Branches of the hepatic artery carry oxygenated blood to the hepatocytes, while branches of the portal vein carry blood with nutrients from the small intestine. The bile duct carries bile products away from the hepatocytes, to the larger ducts and gall bladder.
Are there any ductules in the portal triad?
one or two small bile ductules of cuboidal epithelium, branches of the bile conducting system. The misnomer “portal triad” traditionally has included only the first three structures, and was named before lymphatic vessels were discovered in the structure.
How did the hepatic tanager get its name?
Named for the male’s dusky reddish upperparts (“hepatic” refers to the liver), this species’ scientific name ( flava) also references the female’s yellow plumage. Hepatic Tanagers occur in much of South and Central America and barely reach the southwestern U.S., where they are common but very little studied.
How much blood is in the hepatic vein?
By the time the blood reaches the liver, a lot of its oxygen is gone. Doctors call this deoxygenated blood. The job of the hepatic veins is to move this blood out of your liver. It’s hard work. At any given time, your liver holds about a pint of blood, or about 1/8th of your body’s total blood.