Guidelines

What is Dyshidrosis Lamellosa sicca?

What is Dyshidrosis Lamellosa sicca?

Background: Keratolysis exfoliativa (KE), also known as dyshidrosis lamellosa sicca, is a palmoplantar dermatosis characterized by air-filled blisters and collarette desquamation. It has been regarded as a subtype of dyshidrotic eczema, a fungal infection or a dermatophytid reaction.

How is Keratolysis Exfoliativa treated?

Aggressive moisturization is one of the most important treatments and is often the safest and most effective treatment modality. Keratolytic creams containing urea, lactic acid, ammonium lactate, or salicylic acid have been the most beneficial treatment for the majority of patients.

What is Keratolysis Exfoliativa?

Keratolysis exfoliativa (KE) is a palmoplantar eruption of air-filled bullae on an erythematous base, which results in lamellar peeling with hallmark superficial collarettes of scale.

How common is Keratolysis Exfoliativa?

Keratolysis exfoliativa is more common during the summer months in about 50% of affected individuals. It may be more common in those with sweaty palms due to localised hyperhidrosis.

Does Keratolysis Exfoliativa go away?

It could take a number of months or even years before sufferers and doctors consider the diagnosis of exfoliative keratolysis. There is no known cure for EK, though there are seasons where the condition is dormant. In EK’s earliest stages, small, air-filled blisters appear on the skin.

How do you get rid of Keratolysis?

To treat your pitted keratolysis, your doctor may prescribe anti-bacterial creams and gels such as erythromycin, clindamycin, or mupirocin. If necessary, they may also prescribe drying agents such as Drysol. Botulinum toxin or iontophoresis may also be prescribed to treat sweating.

Is Keratolysis Exfoliativa hereditary?

PSS is caused by genetic variants in several different genes and is inherited in an autosomal recessive pattern of inheritance. PSS is diagnosed based on the symptoms. Other more common conditions may need to be excluded.

What happens if you dont treat pitted keratolysis?

Without treatment, the pits can join together to form a large crater-like lesion. Pitted keratolysis can also cause an unpleasant smell, but people do not usually experience any redness or swelling because this condition is not an inflammatory skin condition. Less commonly, the infection can affect the hands.