What is blood test CCP?
What is blood test CCP?
Cyclic citrullinated peptide (CCP) antibody testing detects and measures CCP antibodies in the blood. CCP antibodies are produced by the immune system and can mistakenly attack healthy tissues. A CCP antibody test requires a blood sample.
What is CCP IgG?
Cyclic Citrullinated Peptide (CCP) Antibody (IgG) – A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from patients with other diseases such as hepatitis C infection.
What’s the difference between RF and anti CCP?
Doctors will also use imaging scans to observe any signs of bone and cartilage deterioration around the affected joints. The anti-CCP test is thought to be slightly more specific than RF for diagnosing rheumatoid arthritis. The reason for this is RF is present in patients without rheumatoid arthritis who have other autoimmune disorders.
What happens if you test positive for CCP but not RF?
If you test positive for anti-CCP antibodies but not rheumatoid factor (RF) and are experiencing any symptoms of the disease, you may have RA. Around 20% of RA patients who test negative for RF will test positive for anti-CCP antibodies [ 24 ]. If you also test positive for RF, you likely have the disease [ 25 ].
When to use a CCP test for rheumatoid arthritis?
A CCP antibody test is used to help diagnose rheumatoid arthritis. It’s often done along with or after a rheumatoid factor (RF) test. Rheumatoid factors are another type of autoantibody. RF tests used to be the main test to help diagnose rheumatoid arthritis.
What should the results of a RF test be?
The results of your RF test will be reported as units per milliliter (u/mL) or the concentration of the antibodies in your blood. Normal levels of RF antibodies in your blood are less than 40 to 60 u/mL, or a concentration under 1:80. Higher numbers indicate a positive RF result.