Is granular mucosa cancerous?

Is granular mucosa cancerous?

Granular cell tumor (GCT), also known as granular cell myoblastoma or Abrikossoff tumor, was initially reported by Abrikossoff in 1926 [1]. It is a soft tissue neoplasm, arising from Schwann cells [2]. Predominantly a benign tumor, 1-2% of the cases are reported to be malignant [3–5].

Is a granular tumor in the esophagus rare?

Esophageal granular cell tumors (GCTs) are rare, often benign tumors of neurogenic origin. GCTs most frequently occur in the skin and subcutaneous tissues but are found in the gastrointestinal (GI) tract in 6%-10% of cases, with the distal two-thirds of the esophagus being the most common site.

How is granular cell tumor diagnosed?

The diagnosis of granular cell tumour is made by skin biopsy. Histopathology reveals characteristic granules within the cytoplasm of large tumour cells. A general medical history and examination to exclude any potentially associated conditions are useful.

What does granular mucosa mean?

Granularity indicates that the surface of mucosa shows unevenness and irregularity, and the degree varies in terms of fineness or roughness.1-3.

What is granular mass?

Summary. Listen. Granular cell tumors (GCTs) are soft tissue tumors that can occur anywhere in the body. They are thought to arise from the cells that surround and insulate the nerve cells in our body (Schwann cells). Most granular cell tumors are benign (non-cancerous), although some may be locally aggressive.

What is a distal esophagitis?

Reflux esophagitis is an esophageal mucosal injury that occurs secondary to retrograde flux of gastric contents into the esophagus. Clinically, this is referred to as gastroesophageal reflux disease (GERD). Typically, the reflux disease involves the distal 8-10 cm of the esophagus and the gastroesophageal junction.

What is granularity in esophagus?

Granular mucosal pattern of the esophagus represents very fine nodularity of the esophageal mucosal surface. This finding is non-specific and may represent: reflux esophagitis (most common) Candida esophagitis.

How common are granular cell tumors?

INTRODUCTION. Granular cell tumours (GrCTs) are uncommon soft tissue tumours that are usually benign (approximately 0.5%–2.0% have been reported as malignant). They are very rarely found at the extremities.

What do granular cells do?

Juxtaglomerular cells (JG cells), also known as granular cells are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.

What is granular mucosa in the colon?

A granular appearance of the colonic mucosa represents edema and small erosions. This is one of the earliest radiographic sign of ulcerative colitis, although in this case it was visible in long-standing disease.