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What is the meaning of nitrosamines?

What is the meaning of nitrosamines?

(ny-TROH-suh-meen) A type of chemical found in tobacco products and tobacco smoke. Nitrosamines are also found in many foods, including fish, beer, fried foods, and meats. Some nitrosamines cause cancer in laboratory animals and may increase the risk of certain types of cancer in humans.

What is a nitrosating agent?

What are Nitrosamines? Nitrosamines are organic substances formed by the reaction of an amine (such as a protein in foods) with a nitrosating agent, such as nitrites that are used as food preservatives. Nitrosamines also form from food in the digestive tract during normal metabolic processes.

What are nitrosamine impurities?

Nitrosamines are a family of carcinogens impurities which are formed by the reaction of secondary amines, amides, carbamates, derivatives of urea with nitrite or other nitrogenous agents with the nitrogen in the +3 state.

What foods contain nitrosamines?

Foods which have been shown to contain volatile nitrosamines include cured meats, primarily cooked bacon; beer; some cheeses; nonfat dry milk; and sometimes fish. It should be emphasized that not all samples analyzed contain detectable amounts of nitrosamines.

What foods are high in nitrosamines?

Are all nitrosamines carcinogenic?

The recent discovery of nitrosamine impurities in several marketed pharmaceuticals has increased interest in their mutagenic and carcinogenic potential. It was found that 18% of nitrosamines were considered non-carcinogenic.

What does nitrosamines do to your body?

Nitrosamines are considered to be strong carcinogens that may produce cancer in diverse organs and tissues including lung, brain, liver, kidney, bladder, stomach, esophagus, and nasal sinus.

What does nitrosamines do to the body?

Where can nitrosamines be found?

Nitrosamines are organic compounds that we are exposed to in our everyday lives. They exist in low levels in our water and foods, including meat, vegetables, and dairy products. Nitrosamines come from chemical reactions and can form in drugs during manufacturing.

How do you prevent nitrosamines?

Eat a diet high in antioxidants. Vitamin C and certain other vitamins can reduce the conversion of nitrates and nitrites to nitrosamines.

What is the medical definition of nitrosamine?

Medical Definition of nitrosamine. : any of various neutral compounds which are characterized by the group NNO and of which some are powerful carcinogens.

How are Nitrosamines formed from amines and nitroso acid?

(nī-trōs’am-ēnz), Amines substituted by a nitroso (NO) group, usually on a nitrogen atom, to yield N-nitrosamines; can be formed by direct combination of an amine and nitrous acid (can be formed from nitrites in the acidic gastric juice); some are mutagenic and/or carcinogenic.

How are nitrosamines used as disinfection by-products?

Nitrosamines may be formed as disinfection by-products when dichloramine in water reacts with available organic matter of either natural or man-made origins. Nitrosamines are considered to be strong carcinogens that may produce cancer in diverse organs and tissues including lung, brain, liver, kidney, bladder, stomach, esophagus, and nasal sinus.

What causes nitrosamines to be found in rumen?

highly hepatotoxic compounds formed in the rumen by the combination of amines and nitrite. They do not appear to occur naturally in large quantities. Nitrosamine poisoning has also been caused by feeding nitrite-treated fishmeal and Solanum incanum.