What is a Zetasizer?

What is a Zetasizer?

The Zetasizer Nano range of instruments provides the ability to measure three characteristic of particles or molecules in a liquid medium. These three fundamental parameters are Particle size, Zeta potential and Molecular weight.

What is zetasizer used for?

Zetasizer systems are used to analyze particle size and zeta potential to improve the appearance and taste of foods, drinks and flavorings, and optimize dispersion and emulsion stability to extend product shelf life and improve product performance.

How is zeta potential measured?

Zeta potential is measured by adding a solution to a cell that contains two gold electrodes. When a voltage is applied to the electrode, the particles will move toward the electrode with the opposite charge. A Doppler technique is used to measure the particle velocity as a function of voltage.

What is the principle of zetasizer?

The principle of dynamic light scattering is that fine particles and molecules that are in constant random thermal motion, called Brownian motion, diffuse at a speed related to their size, smaller particles diffusing faster than larger particles.

What is the Z average?

The Z average is the intensity weighted mean hydrodynamic size of the ensemble collection of particles measured by dynamic light scattering (DLS).

How do you measure particle size?

The most common techniques to determine particle size distribution are dynamic image analysis (DIA), static laser light scattering (SLS, also called laser diffraction), dynamic light scattering (DLS) and sieve analysis.

How does Malvern Zetasizer work?

The Zetasizer Nano series performs molecular weight measurements using a process called Static Light Scattering (SLS). In a similar way to Dynamic Light Scattering – the size theory – the particles in a sample are illuminated by a light source such as a laser, with the particles scattering the light in all directions.

Why zeta potential is negative?

In aqueous media, the pH of the sample is one of the most important factors that affects its zeta potential. Imagine a particle in suspension with a negative zeta potential. If more alkali is added to this suspension then the particles tend to acquire more negative charge.

How is particle size determined?

The most common techniques to determine particle size distribution are dynamic image analysis (DIA), static laser light scattering (SLS, also called laser diffraction), dynamic light scattering (DLS) and sieve analysis. DIA, SLA and sieving, for example, all can measure particles in a range from 1 µm to 3 mm.

What does peak size mean?

The size of the peak has two implications, one it is a measure of the oscillator strength of the transition involving the vibration and second, on a quantitative aspect the size of the peak , i.e the peak area is proportional to the concentration of the analyte which is responsible for the peak observed.

What kind of measurements can a zetasizer do?

The Zetasizer system also has the ability to perform Autotitration measurements and Trend measurements, including the determination of the Protein melting point.  Particle size – NIBS technology enables measurements of particles and molecules from 0.6nm to 8.9 microns.

What kind of plastic is used in zetasizer?

ZEN0118Disposable polystyrene low volume cuvette – for size and molecular weight (90° instruments only). ZEN0040Disposable plastic, micro cuvette, for size measurement at a 173° scattering angle. PCS8501Square glass cell with cap (round aperture) – for size and molecular weight.

How big is a zsu1002 zetasizer particle size?

It is for batch measurements using standard polystyrene or glass cuvettes. Our low volume disposable sizing cell (ZSU1002) design is unique in offering easy-fill, ultra-low volume size measurement in as little as 3 μL. Save time and effort by measuring zeta potential with little or no dilution.

Which is Zeta system for particle size and molecular weight measurement?

The Zetasizer Nano S is a research grade dynamic light scattering system for sub-micron particle and molecular size and molecular weight measurement that combines performance and versatility with exceptional ease of use. The system can be upgraded to add zeta potential capability at a later date. Microrheology measurement Enhancements.