What are Plendil tablets used for?
Plendil is used in the treatment of high blood pressure (hypertension) and heart and chest pain brought on by for example exercise or stress (angina pectoris). if you are pregnant. You should tell your doctor as soon as possible if you become pregnant while using this medicine.
What are the side effects of felodipine 5mg?
5. Side effects
- flushing (feeling hot)
- a pounding heartbeat.
- swollen ankles.
What is the side effects of Plendil?
Common side effects of Plendil include:
- flushing, or.
- stomach upset as your body adjusts to the medication.
When does felodipine peak?
Following oral administration, felodipine is almost completely absorbed and undergoes extensive first-pass metabolism. The systemic bioavailability of PLENDIL is approximately 20%. Mean peak concentrations following the administration of PLENDIL are reached in 2.5 to 5 hours.
What is the average blood pressure for a 70 year old?
They’re both measured in millimetres of mercury (mmHg). As a general guide: high blood pressure is considered to be 140/90mmHg or higher (or 150/90mmHg or higher if you’re over the age of 80) ideal blood pressure is usually considered to be between 90/60mmHg and 120/80mmHg.
Does felodipine affect kidneys?
Felodipine decreases total renal vascular resistance and causes a transient increase in RBF in patients with normal RBF. In patients with low pretreatment values, RBF is increased during chronic treatment. Felodipine does not affect normal GFR.
Is felodipine bad for kidneys?
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure.
How long does felodipine stay in your system?
The half-life of felodipine in the elimination phase is approximately 25 hours and steady state is reached after 5 days. There is no risk of accumulation during long-term treatment. About 70% of a given dose is excreted as metabolites in the urine; the remaining fraction is excreted in the faeces.
What are the long term effects of taking felodipine?
If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks.
What are the ingredients in the tablet Plendil?
Tablets Plendil 5 mg and 10 mg — cellulose, red and yellow oxide, lactose, polyethylene glycol, sodium stearyl fumarate, titanium dioxide, and other ingredients. Felodipine is a member of the dihydropyridine class of calcium channel antagonists (calcium channel blockers).
How many mg of felodipine is in a Plendil tablet?
It is insoluble in water and is freely soluble in dichloromethane and ethanol. Felodipine is a racemic mixture. Tablets PLENDIL provide extended release of felodipine. They are available as tablets containing 2.5 mg, 5 mg, or 10 mg of felodipine for oral administration.
What are the side effects of 20 mg of Plendil?
Corresponding values in hypertensive patients (mean age 64) after a 20-mg dose of Plendil were 23 and 7 nmol/L.
How often should you take Plendil in a day?
Plendil Dosage. The recommended starting dose is 5 mg once a day. Depending on the patient’s response, the dosage can be decreased to 2.5 mg or increased to 10 mg once a day. These adjustments should occur generally at intervals of not less than 2 weeks. The recommended dosage range is 2.5−10 mg once daily.