Is Polymicrogyria a disability?
Is Polymicrogyria a disability?
Polymicrogyria most often occurs as an isolated feature, although it can occur with other brain abnormalities. It is also a feature of several genetic syndromes characterized by intellectual disability and multiple birth defects.
Is Polymicrogyria curable?
The Polymicrogyria (PMG) malformation cannot be reversed, but the symptoms may be treated in children and adults. The first-line treatment for persons with seizures is anti-seizure medications, and the medication chosen depends on the type of seizures or epilepsy syndrome.
What is the life expectancy of polymicrogyria?
The quality of life and life expectancy for people with BPP are not well-described but may depend on severity of symptoms, whether complications develop, and whether other birth defects or an underlying syndrome are present.
When does polymicrogyria develop?
This abnormality can affect either one region of the brain or multiple regions. The time of onset has yet to be identified; however, it has been found to occur before birth in either the earlier or later stages of brain development.
What is frontal polymicrogyria?
Listen. Bilateral frontal polymicrogyria is one of the rarest subtypes of polymicrogyria. It is a symmetric and bilateral form (in both brain hemispheres) that only involves the frontal lobes without including the area located behind the Sylvius fissure or the area located behind the Rolando sulcus.
What is Miller dieker syndrome?
Miller-Dieker syndrome (MDS) is a genetic condition characterized by a specific brain malformation (lissencephaly); distinctive facial features; and severe neurologic abnormalities including intellectual disability and seizures.
What do you need to know about polymicrogyria?
Summary Summary. Polymicrogyria is a condition characterized by abnormal development of the brain before birth. Specifically, the surface of the brain develops too many folds which are unusually small.
What kind of brain disorder is polymicrogyria?
Polymicrogyria is a condition characterized by abnormal development of the brain before birth.
How does polymicrogyria relate to grey matter heterotopias?
Polymicrogyria is one of many malformations of cortical development (see classification system for cortical malformations), and along with grey matter heterotopias, falls under a bewildering group of conditions characterized by abnormalities both in migration of neurons to the cortex and abnormal cortical organization.
Which is ion channels are associated with polymicrogyria?
An association with the gene WDR62 and SCN3A has been identified., as well as other ion channels . Polymicrogyria is a disorder of neuronal migration, resulting in structurally abnormal cerebral hemispheres. The Greek roots of the name describe its salient feature: many [poly] small [micro] gyri (convolutions in the surface of the brain).
