Is Crouzon genetic?
Is Crouzon genetic?
Crouzon syndrome is a rare genetic disorder. It is a form of craniosynostosis, a condition in which there is premature fusion of the fibrous joints (sutures) between certain bones of the skull. The sutures allow an infant’s head to grow and expand.
Is Crouzon syndrome dominant or recessive?
Craniofacial dysostosis, the Crouzon syndrome, occurs sporadically and in families; the clearly heritable form up to now has been autosomal dominant. We ascertained two similarly affected sibs, a brother and a sister, in a sibship of nine.
Can Apert syndrome be passed onto offspring?
Apert syndrome is an autosomal dominant condition, meaning that only one parent needs to have an abnormal gene for the child to inherit the disease. The children of a parent with Apert syndrome have a 50% chance of passing this mutation on to their children.
Can Crouzon syndrome be cured?
How is it treated? Children with mild Crouzon syndrome may not need to be treated. Those with more severe cases should see craniofacial specialists, doctors who treat disorders of the skull and face. In more severe cases, doctors can perform surgery to open up the sutures and give the brain room to grow.
What kind of genetic disorder is Crouzon syndrome?
Crouzon syndrome is a rare genetic disorder. It is a form of craniosynostosis, a condition in which there is premature fusion of the fibrous joints (sutures) between certain bones of the skull.
How is Crouzon syndrome related to Apert syndrome?
6-year-old with Crouzon syndrome with prominent eyes and sunken midface. Crouzon syndrome presents many of the same associated issues as Apert syndrome, including airway compromise, sleep apnea, hydrocephalus and eye exposure issues.
How does Crouzon syndrome affect the head and face?
The head and face of a child with Crouzon syndrome look different because of craniosynostosis —the early closing of the soft, fibrous seams between the skull bones (sutures). Crouzon syndrome often affects the coronal sutures that go over the top of the head from ear to ear.
Can you prevent having a child with Crouzon syndrome?
With advanced planning and appropriate testing, it may be possible to prevent having a child with Crouzon syndrome. If the genetic change ( mutation ) in an affected family member has been identified, prenatal genetic testing may be possible during pregnancy.